Scientists at the University of Glasgow wanted to develop a way to improve therapy that induces cancer-cell killing while also mitigating unwanted toxicity.
Currently, most anti-cancer therapies (chemotherapy, radiation and immunotherapy) work by killing cancer cells through a process called apoptosis, which activates proteins called caspases, leading to cell death.
The new method of killing cancer cells – called Caspase Independent Cell Death (CICD), and published today in Nature Cell Biology, led to the complete eradication of tumours in experimental models.
To read the full article click and watch an explanatory video for the lead author, Dr Stephen Tait, click here